|Research Day Award Winners 2012|
Congratulations to the winners of our Future Physician Scientist Awards! We currently have 3 winners: Joseph Taylor, Cody Rutledge, and Alexander Garcia, with more awards coming soon.
Joseph Taylor won a $100 award and certificate at the Medical University of South Carolina (MUSC) 2012 Research Day on November 2nd.
Joseph Taylor is a 6th year MD/PhD student at the Medical University of South Carolina (MUSC). Prior to MUSC, his research focused on in vivo rodent neurophysiological studies of learning and memory (Davidson College) and movement disorders (NINDS). Mr. Taylor is currently conducting his dissertation research in the Brain Stimulation Laboratory under the direction of Mark S. George, MD. He uses transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (fMRI) to investigate the top-down circuits involved in pain processing. More broadly, Mr. Taylor is interested in using invasive and non-invasive brain stimulation to probe neural circuitry and treat neuropsychiatric disorders.
Two students, Cody Rutledge and Alexander Garcia, won $50 awards and certificates at the University of Illinois at Chicago's College of Medicine 2012 Research Forum on November 16th, 2012.
Cody Rutledge is studying connexin43 in cardiomyocytes. Connexin43 (Cx43) is the main gap junction protein responsible for current propagation in ventricular cardiomyocytes. Cx43 is known to be dysregulated in ischemic heart disease, and decreased Cx43 expression slows the electrical conduction across the ventricles, creating the potential for arrhythmias. Recently, the tyrosine kinase c-Src has been implicated in Cx43 regulation. Phosphorylated, active c-Src (p-c-Src) has a high binding affinity for the scaffolding protein ZO-1. ZO-1 is critical for maintaining Cx43 integrity at the gap junction. When p-c-Src binds to ZO-1, Cx43 is degraded. His project aims to investigate the protective effects of p-c-Src inhibition on models of ischemic heart disease, as well as elucidating the mechanism by which ischemia leads to p-Src activation. He did his undergraduate work at Case Western Reserve University, and currently is in the department of physiology and biophysics, working with Dr. D. Lewandowski.
Be on the lookout for more awards this spring and check out APSA's website for more information on how to become an APSA member and find funding opportunities.